High prevalence of subjective cognitive decline in older Chinese adults: a systematic review and meta-analysis

作者：Chao Xue, Juan Li, Mingqing Hao, Lihua Chen, Zuoxiu Chen, Zeli Tang, Huan Tang, Qian Fang · 发表于：Frontiers in Public Health · 年份：2023 · DOI：10.3389/fpubh.2023.1277995 · 被引用次数：28 · 研究领域：Dementia and Cognitive Impairment Research、Neurological Disease Mechanisms and Treatments、Alzheimer's disease research and treatments

Background: Subjective cognitive decline (SCD) is considered a preclinical stage of Alzheimer's disease. However, reliable prevalence estimates of SCD in the Chinese population are lacking, underscoring the importance of such metrics for policymakers to formulate appropriate healthcare strategies. Objective: To systematically evaluate SCD prevalence among older Chinese adults. Methods: PubMed, Web of Science, The Cochrane Library, Embase, CNKI, Wanfang, VIP, CBM, and Airiti Library databases were searched for studies on SCD in older Chinese individuals published before May 2023. Two investigators independently screened the literature, extracted the information, and assessed the bias risk of the included studies. A meta-analysis was then conducted using Stata 16.0 software via a random-effects model to analyze SCD prevalence in older Chinese adults. Results: A total of 17 studies were included (n = 31,782). The SCD prevalence in older Chinese adults was 46.4% (95% CI, 40.6-52.2%). Further, subgroup analyzes indicated that SCD prevalence was 50.8% in men and 58.9% among women. Additionally, SCD prevalence in individuals aged 60-69, 70-79, and ≥ 80 years was 38.0, 45.2, and 60.3%, respectively. Furthermore, SCD prevalence in older adults with BMI <18.5, 18.5-24.0, and > 24.0 was 59.3, 54.0, and 52.9%, respectively. Geographically, SCD prevalence among older Chinese individuals was 41.3% in North China and 50.0% in South China. In terms of residence, SCD prevalence was 47.1% in u...