Micropattern‐Based Stem Cell Gym: Mechanical Memory Enhanced Stemness Maintenance of Human Dental Pulp Stem Cells and Nerve Regeneration (Adv. Funct. Mater. 49/2023)

作者：Chi-Yu Li, Fanqi Meng, Zhijie Yang, Jiang Peng, Yuwei Guo, Jing Na, Qiusheng Shi, Yu Liu, Yu Wang, Lisha Zheng, Yubo Fan · 发表于：Advanced Functional Materials · 年份：2023 · DOI：10.1002/adfm.202370292 · 被引用次数：3 · 研究领域：3D Printing in Biomedical Research、Mesenchymal stem cell research

Stem Cell Gym In article number 2302829, Yu Wang, Lisha Zheng, Yubo Fan, and co-workers develop a micropatterned based stem cell gym to train dental pulp stem cells for stemness maintenance. The micropattern based gym with 1024 μm2 and aspect ratios of 1:2 and 1:4 effectively enhances the stemness and rescues the pluripotency of stem cells during long-term expansion. The stem cell gym-induced mechanical memory also promotes nerve regeneration in vivo.