Trends in Prevalence of Cannabis Use Disorder Among U.S. Veterans With and Without Psychiatric Disorders Between 2005 and 2019

作者：Ofir Livne, Carol A. Malte, Mark Olfson, Melanie M. Wall, Katherine M. Keyes, Charles Maynard, Jaimie L. Gradus, Andrew J. Saxon, Sílvia S. Martins, Salomeh Keyhani, Yoanna E. McDowell, David S. Fink, Zachary L. Mannes, Sarah Gutkind, Deborah S. Hasin · 发表于：American Journal of Psychiatry · 年份：2023 · DOI：10.1176/appi.ajp.20230168 · 被引用次数：16 · 研究领域：Cannabis and Cannabinoid Research、Substance Abuse Treatment and Outcomes、Opioid Use Disorder Treatment

OBJECTIVE: Cannabis use disorder diagnoses are increasing among U.S. adults and are more prevalent among people with comorbid psychiatric disorders. Recent changes in cannabis laws, increasing cannabis availability, and higher-potency cannabis may have placed people with cannabis use and psychiatric disorders at disproportionately increasing risk for cannabis use disorder. The authors used Veterans Health Administration (VHA) data to examine whether trends in cannabis use disorder prevalence among VHA patients differ by whether they have psychiatric disorders. METHODS: VHA electronic health records from 2005 to 2019 (N range, 4,332,165-5,657,277) were used to identify overall and age-group-specific (<35, 35-64, and ≥65 years) trends in prevalence of cannabis use disorder diagnoses among patients with depressive, anxiety, posttraumatic stress, bipolar, or psychotic spectrum disorders and to compare these to corresponding trends among patients without any of these disorders. Given transitions in ICD coding, differences in trends were tested within two periods: 2005-2014 (ICD-9-CM) and 2016-2019 (ICD-10-CM). RESULTS: Greater increases in prevalence of cannabis use disorder diagnoses were observed among patients with psychiatric disorders compared to those without (difference in prevalence change, 2005-2014: 1.91%, 95% CI=1.87-1.96; 2016-2019: 0.34%, 95% CI=0.29-0.38). Disproportionate increases in cannabis use disorder prevalence among patients with psychiatric disorders were gr...