Synthesis of α-sulfenylated carbonyl compounds under metal-free conditions

作者：Dan Mou, Yuanyuan Wu, Linda Wang, Ying Fu, Zhengyin Du · 发表于：Organic & Biomolecular Chemistry · 年份：2023 · DOI：10.1039/d3ob01796f · 被引用次数：5 · 研究领域：Sulfur-Based Synthesis Techniques、Chemical Synthesis and Reactions、Catalytic C–H Functionalization Methods

An efficient synthesis of α-sulfenylated carbonyl compounds from propargylic alcohols and aryl thiols under heating conditions is described. The method is characterized by mild conditions, simple operation, metal-free catalysis and good functional group tolerance. Mechanistic studies suggest that the reaction involves a radical pathway and an isomerization process.