Physical Activity, Depression and Quality of Life in COPD – Results from the CLARA II Study

作者：Andreas Horner, Horst Olschewski, Sylvia Hartl, Arschang Valipour, Georg‐Christian Funk, Michael Studnicka, Monika Merkle, Bernhard Kaiser, Eva Wallner, Stephan Brecht, Bernd Lamprecht · 发表于：International Journal of COPD · 年份：2023 · DOI：10.2147/copd.s435278 · 被引用次数：25 · 研究领域：Chronic Obstructive Pulmonary Disease (COPD) Research、Cardiac Health and Mental Health、Cardiovascular Health and Risk Factors

Background: Symptoms of depression, pain and limitations in physical activity may affect quality of life in COPD patients independent from their respiratory burden. We aimed to analyze the associations of these factors in outpatients with COPD in Austria in a stable phase of disease. Methods: We conducted a national, cross-sectional study among patients with COPD. For depression, the Patient Health Questionnaire-9 (PHQ-9) and for respiratory symptoms the St. George's Respiratory Questionnaire for COPD patients (SGRQ-C) were used along with 10-point scales for physical activity and pain. Results: %pred. 54.3 ± 16.5 (SD)) were analyzed. Of these, 47% reported one or more exacerbations in the previous year, 10.4% with hospitalization. A negative depression score was found in 54% and a score suggesting severe depression (PHQ-9 score ≥ 15) in 4.7%. In a multivariate linear regression model, self-reported pain, dyspnea, and number of exacerbations were predictors for higher PHQ-9-scores. A negative pain score was found in 43.8%, and a score suggesting severe pain in 2.9% (8-10 points of 10-point scale). Patients reporting severe pain were more often female, had more exacerbations, and reported more respiratory and depressive symptoms, a lower quality of life, and less physical activity. About 46% of patients rated their physical activity as severely impaired. These patients were significantly older, had more exacerbations, concomitant heart disease, a higher pain and depression sco...