SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis

作者：Xiaoyan Li, Sisi Tao, Zhiquan Xu, Yi Ren, Wei Xiang, Xiaojie He · 发表于：Autoimmunity · 年份：2023 · DOI：10.1080/08916934.2023.2281235 · 被引用次数：19 · 研究领域：interferon and immune responses、Inflammasome and immune disorders、Systemic Lupus Erythematosus Research

. In short, SMURF1 upregulation activated the cGAS/STING/IFN-1 signal axis by regulating YY1 ubiquitination to facilitate apoptosis in podocytes during LN progression.