Effects of mosquito control using the microbial agent Bacillus thuringiensis israelensis (Bti) on aquatic and terrestrial ecosystems: a systematic review

作者：Magnus Land, Mirco Bundschuh, Richard Hopkins, Brigitte Poulin, Brendan G. McKie · 发表于：Environmental Evidence · 年份：2023 · DOI：10.1186/s13750-023-00319-w · 被引用次数：29 · 研究领域：Insect Resistance and Genetics、Insect symbiosis and bacterial influences、Studies on Chitinases and Chitosanases

BACKGROUND: The bacterium Bacillus thuringiensis serovar israelensis (Bti) is commercially produced in various formulations for use as a larvicide worldwide, targeting especially the aquatic larval stage of mosquitoes. However, there is a concern that repeated Bti treatments may have both direct and indirect impacts on non-target organisms (NTOs) and the ecosystems they inhabit. This review evaluates the evidence for such impacts. METHODS: Literature was searched using six bibliographic databases, two search engines, and on specialist web sites. Eligibility screening was performed in two steps on (1) title/abstract, with consistency among reviewers assessed by double-screening 557 articles and (2) full text. Articles included after full text screening were critically appraised independently by two reviewers. Disagreements were reconciled through discussions. Key parameters of included studies are presented in narrative synthesis tables, including risk of bias assessments. Meta-analyses comparing treated with untreated ecosystems and using either the raw mean difference or log response ratio as effect size were performed. REVIEW FINDINGS: . Our metanalyses revealed a consistent negative effect of Bti treatment on abundances of Chironomidae and Crustacea, and also on chironomid emergence, although from a more restricted set of studies and regions. For most remaining response variables, we judged meta-analysis unfeasible, due to low study numbers or insufficient reporting of met...