The Characteristics, Mechanisms and Therapeutics: Exploring the Role of Gut Microbiota in Obesity

作者：Zequn Zhuang, Peng Zhou, Jing Wang, Xiaojing Lu, Yigang Chen · 发表于：Diabetes Metabolic Syndrome and Obesity · 年份：2023 · DOI：10.2147/dmso.s432344 · 被引用次数：33 · 研究领域：Gut microbiota and health、Diet and metabolism studies、Dietary Effects on Health

Presently, obesity has emerged as a significant global public health concern due to its escalating prevalence and incidence rates. The gut microbiota, being a crucial environmental factor, has emerged as a key player in the etiology of obesity. Nevertheless, the intricate and specific interactions between obesity and gut microbiota, along with the underlying mechanisms, remain incompletely understood. This review comprehensively summarizes the gut microbiota characteristics in obesity, the mechanisms by which it induces obesity, and explores targeted therapies centered on gut microbiota restoration.