Elevated 68Ga-FAPI-04 Activity Due to Staphylococcus aureus Intracranial Infection

作者：Zeyu Zhang, Wen‐Li Hou, Guixia Pan, Changjing Zuo, Chao Cheng · 发表于：Clinical Nuclear Medicine · 年份：2023 · DOI：10.1097/rlu.0000000000004958 · 被引用次数：10 · 研究领域：Peptidase Inhibition and Analysis、Protease and Inhibitor Mechanisms、Signaling Pathways in Disease

ABSTRACT: A 37-year-old man was admitted to our hospital after experiencing syncope. An MRI of his head revealed multiple foci of abnormal signal, which could potentially be metastases. The patient then underwent a 68 Ga-FAPI-04 PET/MRI examination, which revealed multiple FAPI-avid foci in the brain. Upon analyzing the cerebrospinal fluid, it was found that the patient had a Staphylococcus aureus infection. The results suggest that 68 Ga-FAPI-04 PET has the potential to be a valuable tool in the visualization of intracranial infectious lesions.