Aroyl-isothiocyanates/isoselenocyanates as precursors to obtain novel cis -3-aroyl-thiourea/urea-β-lactams: design, synthesis, docking and biological evaluation

作者：Pankaj Kumar, Jaswinder Kaur, Sumeeta Kumari, Sakshi Paliwal, Shiwani Berry, Anil Kumar Pinnaka, Aman Bhalla · 发表于：New Journal of Chemistry · 年份：2023 · DOI：10.1039/d3nj04485h · 被引用次数：10 · 研究领域：Synthesis of β-Lactam Compounds、Synthesis and Catalytic Reactions、Organic Chemistry Cycloaddition Reactions

Herein, a novel synthetic methodology was devised to synthesize cis -3-aroyl-thiourea/urea-β-lactams by reacting aroyl isothiocyanates/isoselenocyanates with cis -3-amino-β-lactams.