Posttraumatic growth EEG neuromarkers: translational neural comparisons with resilience and PTSD in trauma-exposed healthy adults

作者：A J Glazebrook, Jane Shakespeare‐Finch, Brooke Andrew, J. van der Meer · 发表于：European Journal of Psychotraumatology · 年份：2023 · DOI：10.1080/20008066.2023.2272477 · 被引用次数：13 · 研究领域：Traumatic Brain Injury Research、Posttraumatic Stress Disorder Research、Resilience and Mental Health

Background: Supporting wellbeing beyond symptom reduction is necessary in trauma care.Research suggests increased posttraumatic growth (PTG) may promote wellbeing more effectively than posttraumatic stress disorder (PTSD) symptom reduction alone.Understanding neurobiological mechanisms of PTG would support PTG intervention development.However, most PTG research to-date has been cross-sectional data selfreported through surveys or interviews.Objective: Neural evidence of PTG and its coexistence with resilience and PTSD is limited.To advance neural PTG literature and contribute translational neuroscientific knowledge necessary to develop future objectively measurable neural-based PTG interventions.Method: Alpha frequency EEG and validated psychological inventories measuring PTG, resilience, and PTSD symptoms were collected from 30 trauma-exposed healthy adults amidst the COVID-19 pandemic.EEG data were collected using custom MNE-Python software, and a wireless OpenBCI 16-channel dry electrode EEG headset.Psychological inventory scores were analysed in SPSS Statistics and used to categorise the EEG data.Power spectral density analyses, t-tests and ANOVAs were conducted within EEGLab to identify brain activity differentiating high and low PTG, resilience, and PTSD symptoms.Results: Higher PTG was significantly differentiated from low PTG by higher alpha power in the left centro-temporal brain area around EEG electrode C3.A trend differentiating high PTG from PTSD was also indicat...