Cohort Profile: The Jiangsu Birth Cohort

作者：Jiangbo Du, Yuan Lin, Yankai Xia, Hongxia Ma, Yangqian Jiang, Chuncheng Lu, Wei Wu, Minjian Chen, Yang Zhao, Juncheng Dai, Guangfu Jin, Jiayin Liu, Jiahao Sha, Hongbing Shen, Zhibin Hu, China National Birth Cohort (CNBC) Study Group, Jørn Olsen, Brenda Eskenazi, Stephanie J. London, Jun Zhang, Cuilin Zhang, Hongbing Shen, Zhibin Hu, Jiahao Sha, Jiayin Liu, Yankai Xia, Feng Chen, Guangfu Jin, Hongxia Ma, Yuan Lin, Jiangbo Du, Feiyang Diao, Yang Zhao, Di Wu, Wei Wu, Chuncheng Lu, Wei Wu, Di Wu, Minjian Chen, Xiumei Han, Bo Xu, Kun Zhou, Rong Shen, Xuemei Jia, Zhengfeng Xu, Xiufeng Ling, Meiling Tong, Xia Chi, Ting Chen, Zhiliang Ding, Hong Li, Qingxia Meng, Kan Ye, Liping Zhu, Boxian Huang, Yanan Wang, Xiaoyan Wang, Zhonghua Shi, Bin Yu, Li Chen, Lingmin Hu, Haiting Hu, Gang Pei, Qi Zhou, Enkui Duan, Hefeng Huang, Zi‐Jiang Chen, Jiong Li · 发表于：International Journal of Epidemiology · 年份：2023 · DOI：10.1093/ije/dyad139 · 被引用次数：37 · 研究领域：Birth, Development, and Health、Pregnancy and preeclampsia studies、Gestational Diabetes Research and Management

The Jiangsu Birth Cohort (JBC) is a family-based prospective cohort in Jiangsu Province, China, consisting of families receiving assisted reproductive technology (ART) treatment or families with spontaneous pregnancies. The study aimed to investigate the differences between the two groups of participants regarding both short- and long-term health outcomes in women and their offspring. The cohort recruited couples who planned to receive ART treatment at ART clinics, and collected data on the ART procedures and outcomes. Spontaneously conceiving couples were recruited during early pregnancy (8–14 weeks of gestation) at obstetrics clinics. Thereafter, ART pregnancies and spontaneous pregnancies were followed throughout the whole gestation with the same protocol. After childbirth, all children were followed until up to 3 years of age. Data on health were collected through standardized and structured questionnaires and medical records, together with biospecimens from both parents and their children. The cohort thus provided a valuable resource for the research on parental and child health associated with ART pregnancies. Between April 2014 and June 2022, the JBC has recruited 7618 ART treated families and 14 996 families of spontaneous completed or ongoing pregnancies. For the families enrolled up to 30 June 2020 (5061 ART families and 12 793 spontaneous conception families), we have completed data from their entry throughout their fertility care (for ART families), pregnancy, bir...