Lubricin (PRG-4) anti-fouling coating for surface-enhanced Raman spectroscopy biosensing: towards a hierarchical separation system for analysis of biofluids

作者：Mingyu Han, Saimon Moraes Silva, Matthew J. Russo, Pauline E. Desroches, Weiwei Lei, Anita Quigley, Robert M. I. Kapsa, Simon E. Moulton, Paul R. Stoddart, George W. Greene · 发表于：The Analyst · 年份：2023 · DOI：10.1039/d3an00910f · 被引用次数：16 · 研究领域：Gold and Silver Nanoparticles Synthesis and Applications、Biosensors and Analytical Detection、Electrochemical Analysis and Applications

, noise) levels and excellent analyte spectral fidelity. These findings indicate the great potential for using LUB coatings together with an analyte-selective layer to form a hierarchical separation system for SERS sensing of relevant analytes directly in complex biological media, aquaculture, food matrix or environmental samples.