Efficacy of repetitive transcranial magnetic stimulation at different sites for peripheral facial paralysis: a prospective cohort study

作者：Zicai Liu, Xin Wen, Yuchun Shao, Zihao Wan, Bangliang Liu, Risheng Wang, Huiyu Liu · 发表于：Frontiers in Neurology · 年份：2023 · DOI：10.3389/fneur.2023.1285659 · 被引用次数：6 · 研究领域：Facial Nerve Paralysis Treatment and Research、Trigeminal Neuralgia and Treatments、Temporomandibular Joint Disorders

Background There are very few studies on transcranial magnetic stimulation (TMS) therapy for facial paralysis and no studies comparing the efficacy of central and peripheral TMS in the treatment of peripheral facial paralysis (PFP). Purpose To observe the therapeutic effect and security of central and peripheral repetitive transcranial magnetic stimulation (rTMS) on PFP. Methods Patients with unilateral onset of peripheral facial paralysis within 1 month were prospectively recruited, 97 patients with PFP were divided into the peripheral group, central group, and control group. The control group was given common treatment (drug therapy and acupuncture), and the peripheral and central groups received rTMS in addition to conventional treatment. After 2 weeks of treatment, the House-Brackmann (HB) grading scale, Sunnybrook facial grading system (SFGS), and modified Portmann scale (MPS) were used to evaluate the facial muscle function of patients in the three groups. Result After 2 weeks of rTMS treatment, the HBGS/SFGS/MPS scores of the three groups were significantly better than before ( p < 0.05), and the mean change values of HBGS, SFGS, and MPS scores were significantly higher in participants in Peripheral Group ( p < 0.001; p < 0.001; p = 0.003; respectively) and Central Group ( p = 0.004; p = 0.003; p = 0.009; respectively) than in Control Group. But the mean change values of HBGS, SFGS, and MPS scores showed no significant differences in participants i...