Experimental models for cancer brain metastasis

作者：Zihao Liu, Shanshan Dong, Mengjie Liu, Yuqiang Liu, Zhiming Ye, Jianhao Zeng, Maojin Yao · 发表于：Cancer Pathogenesis and Therapy · 年份：2023 · DOI：10.1016/j.cpt.2023.10.005 · 被引用次数：17 · 研究领域：Brain Metastases and Treatment、Lung Cancer Research Studies、Glioma Diagnosis and Treatment

models, including cultured cells using the Transwell system, organoids, microfluidic models, syngeneic models, xenograft models, and genetically engineered models. We have also provided a concise summary of the merits and limitations inherent to each model while identifying the optimal contexts for their effective utilization. This review serves as a comprehensive resource, aiding researchers in making well-informed decisions regarding model selection that align with specific research questions.