Preoperative Treatment of Locally Advanced Rectal Cancer

作者：David Sebag-Montefiore, Andrés Cervantes, Claus Michael Rödel · 发表于：New England Journal of Medicine · 年份：2023 · DOI：10.1056/nejmc2309857 · 被引用次数：13 · 研究领域：Colorectal Cancer Surgical Treatments、Gastric Cancer Management and Outcomes、Colorectal and Anal Carcinomas

To the Editor: I congratulate Schrag et al. (July 27 issue) 1 for successful completion of the PROSPECT trial (Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients with Locally Advanced Rectal Cancer Undergoing Surgery). A major disappointment was the low percentage of Black participants — 4% of the total. Although a wide racial gap persists between Black patients and White patients in colorectal cancer (with Black patients having a 20% higher incidence and 40% higher mortality), Black participation in cancer trials remains low. A major reason is lack of trust. This mistrust isn’t solely related to historical ethical maltreatment . . .