Prevalence and influencing factors of abnormal carotid artery intima-media thickness in Henan Province in China

作者：Tingting Yang, Yating Wang, Xiaoke Zhang, Siyun Xiang, Jing Wen, Wen Wang, Ke Guan, Weixiang Wang, Yang Yang, Liuwei Hao, Yongchun Chen · 发表于：Frontiers in Endocrinology · 年份：2023 · DOI：10.3389/fendo.2023.1266207 · 被引用次数：4 · 研究领域：Cardiovascular Health and Disease Prevention、Blood Pressure and Hypertension Studies、Sodium Intake and Health

Background Carotid intima-media thickness (CIMT) has been shown to be a valuable predictor of cardiovascular diseases (CVDs). The aim of this study was to investigate the influencing factors of CIMT among adults in Central China. Methods A total of 2,578 participants who underwent physical examination in Henan Provincial People’s Hospital between January 2018 and July 2018 were enrolled. The respondents were divided into two subgroups according to their CIMT value (CIMT ≥1.0 mm group and CIMT <1.0 mm group). Variables considered were age, gender, total cholesterol, triglycerides, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) triglycerides, fasting blood glucose, and uric acid levels, as well as hypertension, diabetes, body mass index (BMI), waist-to-hip ratio, body fat percentage, and visceral fat area (VFA). Logistic regression analysis was performed to explore the potential factors influencing CIMT. Results The proportion of CIMT ≥1.0 mm among the physical examination population was 27.42% (707/2 578). The analysis of the two groups revealed significant differences in age, sex, hypertension, diabetes, total cholesterol, and HDL cholesterol. In the logistic regression analysis, age ( OR =1.071, 95% CI =1.062–1.080), male sex ( OR =2.012, 95% CI =1.251–2.238), hypertension ( OR =1.337, 95% CI =1.031–1.735), diabetes ( OR =1.535, 95% CI =1.045–2.255), HDL cholesterol ( OR =0.540, 95% CI =0.366–0.796), and LDL cholesterol ( OR =1.336, 95% CI =1.154–1.5...