Stabilized cyclic peptides as modulators of protein–protein interactions: promising strategies and biological evaluation

作者：Jiongjia Cheng, Junlong Zhou, Lingyan Kong, Hai‐Ying Wang, Yuchi Zhang, Xiaofeng Wang, Guang‐Xiang Liu, Qian Chu · 发表于：RSC Medicinal Chemistry · 年份：2023 · DOI：10.1039/d3md00487b · 被引用次数：35 · 研究领域：Chemical Synthesis and Analysis、Click Chemistry and Applications、Biochemical and Structural Characterization

development of cyclic peptide ligands with pharmacological properties. In summary, the development of cyclic peptide-based PPI modulators carries tremendous promise for the next generation of therapeutic agents to target historically "intractable" PPI systems.