Global, regional, and national burden of spinal cord injury, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

作者：Mahdi Safdarian, Eugen Trinka, Vafa Rahimi‐Movaghar, Aljoscha C. Thomschewski, Amirali Aali, Gdiom Gebreheat Abady, Semagn Mekonnen Abate, Foad Abd-Allah, Aidin Abedi, Denberu Eshetie Adane, Saira Afzal, Bright Opoku Ahinkorah, Sajjad Ahmad, Haroon Ahmed, Nasir Amanat, Dhanalakshmi Angappan, Jalal Arabloo, Armin Aryannejad, Seyyed Shamsadin Athari, Alok Atreya, Sina Azadnajafabad, Ahmed Y. Azzam, Hassan Babamohamadi, Palash Chandra Banik, Mainak Bardhan, Azadeh Bashiri, Alemshet Yirga Berhie, Ajay Nagesh Bhat, Julie K Brown, Ana Paula Silva Champs, Periklis Charalampous, Isaac Sunday Chukwu, Kaleb Coberly, Omid Dadras, Dereje Y Yada, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Fikadu Nugusu Dessalegn, Abebaw Alemayehu Desta, Sameer Dhingra, Nancy Diao, Daniel Díaz, Mahmoud Dibas, Deepa Dongarwar, Haneil Larson Dsouza, Michael Ekholuenetale, Nevine M. El Nahas, Muhammed Elhadi, Sharareh Eskandarieh, Adeniyi Francis Fagbamigbe, Jawad Fares, Ali Fatehizadeh, Seyed‐Mohammad Fereshtehnejad, Florian Fischer, Richard Charles Franklin, Tushar Garg, Melaku Getachew, Fariborz Ghaffarpasand, Ali Gholamrezanezhad, Milad Gholizadeh Mesgarha, Sherief Ghozy, Mahaveer Golechha, Pouya Goleij, Simon Matthew Graham, Vivek Gupta, Juanita A. Haagsma, Samer Hamidi, Netanja I. Harlianto, Mehdi Harorani, Mohammad Hasanian, Amr Hassan, Mohammed Bheser Hassen, Amir Human Hoveidaei, Farideh Iravanpour, Rana Irilouzadian, Chidozie C D Iwu, Louis Jacob, Chinwe Juliana Jaja, Nitin Joseph, Charity Ehimwenma Joshua, Jacek Jerzy Jozwiak, Vidya Kadashetti, Amit Kandel, Rami S. Kantar, Ibraheem M. Karaye, Samad Karkhah, Yousef Saleh Khader, Ejaz Ahmad Khan, Mohammad Jobair Khan, Hamid Reza Khayat Kashani, Mohammad Saeid Khonji, Moein Khormali, Grace Kim, Vijay K. Krishnamoorthy, Senthil D Kumaran, Mohammad‐Reza Malekpour, Tuomo J Meretoja, Mohamed Kamal Mesregah, Tomislav Meštrović, Ana Carolina Micheletti Gomide Nogueira de Sá, Ted R. Miller, Alireza Mirahmadi, Peyman Mirghaderi, Moonis Mirza, Awoke Misganaw, Sanjeev Misra, Yousef M. Mohammad, Esmaeil Mohammadi, Ali H. Mokdad, Holger Möller, Sara Momtazmanesh, Mohammad Ali Moni, Ebrahim Mostafavi, Francesk Mulita, Mohsen Naghavi, Hasan Nassereldine, Zuhair Saleh Natto, Kazem Nejati‐Koshki, Huong Lan Thi Nguyen, Văn Thành Nguyễn, Antonio Tolentino Nogueira de Sá, Andrew T Olagunju, Isaac Iyinoluwa Olufadewa, Abiodun Olusola Omotayo, Mayowa Ojo Owolabi, Shankargouda Patil, Shrikant S. Pawar, Paolo Pedersini, Ionela-Roxana Petcu, Suzanne Polinder, Ali Mohammad Pourbagher‐Shahri, Maryam Faiz Qureshi, Pankaja Raghav Raghav, Mosiur Rahman, Niloufar Rahnavard, Ali Rajabpour-Sanati, Mohammad‐Mahdi Rashidi, Salman Rawaf, Nicholas L S Roberts, Basema Saddik, Umar Abid Saeed, Sara Samadzadeh, Abdallah M Samy, Arash Sarveazad, Allen Seylani, Mahan Shafie, Ataollah Shahbandi, Mequannent Melaku Sharew Sharew, Rahim Ali Sheikhi, Pavanchand H Shetty, Arzu Yiğit, Parnian Shobeiri, Sina Shool, Seyed Afshin Shorofi, Migbar Mekonnen Sibhat, Ehsan Sinaei, Paramdeep Singh, Surjit Singh, Yonatan Solomon, Houman Sotoudeh, Belsti Atnkut Tadesse, Muhammad Umair, Sahel Valadan Tahbaz, Pascual Ruben Valdez, Narayanaswamy Venketasubramanian, Linh Gia Vu, Nuwan Darshana Wickramasinghe, Iman Zare, Fereshteh Yazdanpanah, Aimin Wu, Zhi‐Jiang Zhang · 发表于：The Lancet Neurology · 年份：2023 · DOI：10.1016/s1474-4422(23)00287-9 · 被引用次数：393 · 研究领域：Spinal Cord Injury Research、Prosthetics and Rehabilitation Robotics、Nerve injury and regeneration

BACKGROUND: Spinal cord injury (SCI) is a major cause of health loss due to premature mortality and long-term disability. We aimed to report on the global, regional, and national incidence, prevalence, and years of life lived with disability (YLDs) for SCI from 1990 to 2019, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. METHODS: Using GBD 2019 data pooled in DisMod-MR 2.1, a Bayesian meta-regression tool, we systematically derived numbers and age-standardised rate changes with 95% uncertainty intervals (95% UIs) for the incidence, prevalence, and YLDs for SCI from 1990 to 2019 for the whole world, 21 GBD regions, and 204 countries and territories. We report trends based on age, sex, year, cause of injury, and level of injury. FINDINGS: Globally, 20·6 million (95% UI 18·9 to 23·6) individuals were living with SCI in 2019. The incidence of SCI was 0·9 million (0·7 to 1·2) cases with an estimated 6·2 million (4·5 to 8·2) YLDs. SCI rates increased substantially from 1990 to 2019 for global prevalence (81·5%, 74·2 to 87·1), incidence (52·7%, 30·3 to 69·8), and YLDs (65·4%, 56·3 to 76·0). However, global age-standardised rates per 100 000 population showed small changes in prevalence (5·8%, 2·6 to 9·5), incidence (-6·1%, -17·2 to 1·5), and YLDs (-1·5%, -5·5 to 3·2). Data for 2019 shows that the incidence of SCI increases sharply until age 15-19 years, where it remains reasonably constant until 85 years of age and older. By contrast, pre...