Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction

作者：Xi Shi, Congyi Lu, Alba Corman, Alexandra Nikish, Yang Zhou, R. Platt, Ivan Iossifov, Feng Zhang, Jen Q. Pan, Neville E. Sanjana · 发表于：The American Journal of Human Genetics · 年份：2023 · DOI：10.1016/j.ajhg.2023.09.004 · 被引用次数：32 · 研究领域：CRISPR and Genetic Engineering、Genomics and Chromatin Dynamics、Autism Spectrum Disorder Research