Mechanical Signal‐Tailored Hydrogel Microspheres Recruit and Train Stem Cells for Precise Differentiation (Adv. Mater. 40/2023)

作者：Zehao Chen, Zhendong Lv, Yaping Zhuang, Qimanguli Saiding, Yang Wu, Wei Xiong, Zhen Zhang, Hao Chen, Wenguo Cui, Yuhui Zhang · 发表于：Advanced Materials · 年份：2023 · DOI：10.1002/adma.202370284 · 被引用次数：31 · 研究领域：Electrospun Nanofibers in Biomedical Applications、Silk-based biomaterials and applications、Tissue Engineering and Regenerative Medicine

Tissue Regeneration In article number 2300180, Hao Chen, Wenguo Cui, Yuhui Zhang, and co-workers propose a hydrogel-microsphere-based synthetic niche with cell recruiting and targeted cell differentiation properties via mechanotransduction. The microsphere niche guides the fate of endogenous stem cells in the aberrant mechanical microenvironment, offering an effective strategy for enhancing the endogenous regeneration of degenerated tissues.