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Gut microbe-derived metabolite indole-3-carboxaldehyde alleviates atherosclerosis

作者:Yijing Lu, Wenlong Yang, Zhiyong Qi, Rifeng Gao, Jing Tong, Tingwen Gao, Yin Zhang, Aijun Sun, Shuning Zhang, Junbo Ge · 发表于:Signal Transduction and Targeted Therapy · 年份:2023 · DOI:10.1038/s41392-023-01613-2 · 被引用次数:49 · 研究领域:Gut microbiota and health、Tryptophan and brain disorders、Diet and metabolism studies

Indole-3-carboxaldehyde (ICA) is a gut microbe-derived tryptophan metabolite. Here, we explored the role of ICA in atherosclerosis.