NBE-Controlled Palladium-Catalyzed Intermolecular Selective C–H Silylation of Boronic Acids

作者：Wenguang Li, Yongqi Yu, Xu Zhang, Chunyan Zhang, Ming Chen, Ting Li · 发表于：The Journal of Organic Chemistry · 年份：2023 · DOI：10.1021/acs.joc.3c01655 · 被引用次数：14 · 研究领域：Catalytic C–H Functionalization Methods、Catalytic Cross-Coupling Reactions、Organoboron and organosilicon chemistry

An efficient palladium-catalyzed intermolecular selective C–H silylation of boronic acids is described. The combination of palladium catalyst with copper oxidant enables ortho -selective C–H silylation by employing hexamethyldisilane as the trimethylsilyl source, which relies on the control of NBE derivatives as a switch, thus providing straightforward access to divergent organosilicon compounds.