Atrial Fibrillation Recurrence in Patients With Transient New-Onset Atrial Fibrillation Detected During Hospitalization for Noncardiac Surgery or Medical Illness
作者:William F. McIntyre, Maria E. Vadakken, Stuart J. Connolly, Pablo Mendoza, A. Lengyel, Anand S. Rai, N. Latendresse, Alex Grinvalds, Chinthanie Ramasundarahettige, J. Gabriel Acosta, Kevin J. Um, Jason D. Roberts, David Conen, Jorge Wong, P.J. Devereaux, Emilie P. Belley‐Côté, Richard Whitlock, Jeff S. Healey · 发表于:Annals of Internal Medicine · 年份:2023 · DOI:10.7326/m23-1411 · 被引用次数:29 · 研究领域:Atrial Fibrillation Management and Outcomes、Cardiac Arrhythmias and Treatments、Heart Failure Treatment and Management
BACKGROUND: Atrial fibrillation (AF) is often detected for the first time in patients who are hospitalized for another reason. Long-term risks for AF recurrence in these patients are unclear. OBJECTIVE: To estimate risk for AF recurrence in patients with new-onset AF during a hospitalization for noncardiac surgery or medical illness compared with a matched population without AF. DESIGN: Matched cohort study. (ClinicalTrials.gov: NCT03221777). SETTING: Three academic hospitals in Hamilton, Ontario, Canada. PARTICIPANTS: The study enrolled patients hospitalized for noncardiac surgery or medical illness who had transient new-onset AF. For each participant, an age- and sex-matched control participant with no history of AF from the same hospital ward was recruited. All participants left the hospital in sinus rhythm. MEASUREMENTS: 14-day electrocardiographic (ECG) monitor at 1 and 6 months and telephone assessment at 1, 6, and 12 months. The primary outcome was AF lasting at least 30 seconds on the monitor or captured by ECG 12-lead during routine care at 12 months. RESULTS: = 40) and their matched control participants and limiting to AF events detected by the patch ECG monitor, recurrent AF was detected in 32.3% (CI, 23.1% to 41.5%) of participants with transient new-onset AF and 3.0% (CI, 0% to 6.4%) of matched control participants. LIMITATIONS: Generalizability is limited, and the study was underpowered to evaluate subgroups and clinical predictors. CONCLUSION: Among patients wh...