Direct organocatalytic transfer hydrogenation and C–H oxidation: high-yielding synthesis of 3-hydroxy-3-alkyloxindoles

作者：Pritam Roy, Shazia Anjum, Shyam D. Sanwal, Dhevalapally B. Ramachary · 发表于：Organic & Biomolecular Chemistry · 年份：2023 · DOI：10.1039/d3ob01264f · 被引用次数：6 · 研究领域：Asymmetric Hydrogenation and Catalysis、Cyclopropane Reaction Mechanisms、Catalytic C–H Functionalization Methods

) analysis. This two-step high-yielding transfer hydrogenation/C-H oxidation protocol was used for the total synthesis of medicinally important 3-cyanomethyl-3-hydroxyoxindole and formal total synthesis of (±)-alline and (±)-CPC-I in very good overall yields compared to previous methods.