Bioactivity and antibacterial properties of zinc-doped Ta2O5 nanorods on porous tantalum surface

作者：Anqi Cai, Hairong Yin, Cuicui Wang, Qian Chen, Yingxuan Song, Ruixue Yin, Xin Yuan, Haoran Kang, Hongwei Guo · 发表于：Biomedical Materials · 年份：2023 · DOI：10.1088/1748-605x/acfbd0 · 被引用次数：7 · 研究领域：Bone Tissue Engineering Materials、Nanoparticles: synthesis and applications、Graphene and Nanomaterials Applications

Abstract This paper focuses on the preparation of Zn 2+ -doped Ta 2 O 5 nanorods on porous tantalum using the hydrothermal method. Porous tantalum is widely used in biomedical materials due to its excellent elastic modulus and biological activity. Porous tantalum has an elastic modulus close to that of human bone, and its large specific surface area is conducive to promoting cell adhesion. Zinc is an important component of human bone, which not only has spectral bactericidal properties, but also has no cytotoxicity. The purpose of this study is to provide a theoretical basis for the surface modification of porous tantalum and to determine the best surface modification method. The surface structure of the sample was characterized by x-ray diffractometer, x-ray photoelectron spectroscopy, scanning electron microscope, transmission electron microscope, and the Zn-doped Ta 2 O 5 nanorods are characterized by antibacterial test, MTT test, ICP and other methods. The sample has good antibacterial properties and no cytotoxicity. The results of this study have potential implications for the development of new and improved biomedical materials.