The role of maternal age on adverse pregnancy outcomes among primiparous women with singleton birth: a retrospective cohort study in urban areas of China

作者：Jiangheng Li, Jingli Yan, Wu Jiang · 发表于：The Journal of Maternal-Fetal & Neonatal Medicine · 年份：2023 · DOI：10.1080/14767058.2023.2250894 · 被引用次数：34 · 研究领域：Maternal and fetal healthcare、Maternal and Perinatal Health Interventions、Pregnancy and preeclampsia studies

Background Both young and advanced maternal age pregnancies have strong associations with adverse pregnancy outcomes; however, there is limited understanding of how these associations present in an urban environment in China. This study aimed to analyze the associations between maternal age and pregnancy outcomes among Chinese urban women.Methods We performed a population-based study consisting of 60,209 singleton pregnancies of primiparous women whose newborns were delivered after 20 weeks’ gestation between January 2012 and December 2015 in urban areas of China. Participants were divided into six groups (19 or younger, 20–24, 25–29, 30–34, 35–39, 40 or older). Pregnancy outcomes include gestational diabetes mellitus (GDM), preeclampsia, placental abruption, placenta previa, premature rupture of membrane (PROM), postpartum hemorrhage, preterm birth, low birthweight, small for gestational age (SGA), large for gestational age (LGA), fetal distress, congenital microtia, and fetal death. Logistic regression models were used to assess the role of maternal age on the risk of adverse pregnancy outcomes with women aged 25–29 years as the reference group.Results The risks of GDM, preeclampsia, placenta previa, and postpartum hemorrhage were decreased for women at a young maternal age and increased for women with advanced maternal age. Both young and advanced maternal age increased the risk of preterm birth and low birthweight. Young maternal age was also associated with increased ris...