Black Phosphorus‐Based Conductive Hydrogels Assisted by Electrical Stimulus for Skin Tissue Engineering

作者：Wenxin Liu, Yingnan Zhu, Zhaofan Tao, Yuxiang Chen, Lei Zhang, Alideertu Dong · 发表于：Advanced Healthcare Materials · 年份：2023 · DOI：10.1002/adhm.202301817 · 被引用次数：35 · 研究领域：Advanced Sensor and Energy Harvesting Materials、Conducting polymers and applications、Polydiacetylene-based materials and applications

Abstract Conductive hydrogels have shown great potential in wound healing and skin tissue engineering, owing to their electroactive, mechanical, and chemical properties. However, it still remains as a challenge to incorporate other functions into conductive hydrogels, such as antibacterial ability, controllable drug release, and biodegradability. In this study, a black phosphorus‐based conductive hydrogel (HA‐DA@BP) is prepared by an amidation reaction coupled with a coordination of Fe 3+ ‐catechol. The hydrogel could be changed from the sol phase to the gel phase under electrical stimulus (ES). The results show that BP could be released under slight acidity, which is cell compatible but could achieve synergistic electrical antibacterial action and promote wound healing. This study proves that BP is a strong candidate for electroactive materials and provides a new insight for the development of BP‐based biomedical materials in skin tissue engineering.