[Clinical characteristics and prognostic factors of patients with anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis associated interstitial lung disease].

作者：Ruyi Zou, Qi Zhao, Yun Tian, Xin Yan, X H Qiu, Y J Gao, Y Liu, Mengxi Huang, Min Cao, Jinghong Dai, Hourong Cai · 发表于：PubMed · 年份：2023 · DOI：10.3760/cma.j.cn112147-20221017-00821 · 被引用次数：3 · 研究领域：Inflammatory Myopathies and Dermatomyositis、Cancer Diagnosis and Treatment、Skin Diseases and Diabetes

The clinical manifestations of patients with anti-MDA5+DM-ILD presenting to the respiratory department were heterogeneous, with most being amyopathic dermatomyositis, and both the incidence of RP-ILD and the risk of death were high. Even in the absence of associated rash, joint, or muscle manifestations, anti-MDA5 antibody screening should be considered in patients with rapidly progressive ILD who were negative on baseline autoantibody screening but positive for anti-RO52kDa antibody.