Detection of low-frequency mutations in clinical samples by increasing mutation abundance via the excision of wild-type sequences

作者：Wei Chen, Haiqi Xu, Shenbin Dai, Jiayu Wang, Wenlong Yang, Yuewen Jin, Mengbing Zou, Xianjin Xiao, Tongbo Wu, Wei Yan, Bin Zhang, Zhimiao Lin, Meiping Zhao · 发表于：Nature Biomedical Engineering · 年份：2023 · DOI：10.1038/s41551-023-01072-8 · 被引用次数：43 · 研究领域：Cancer Genomics and Diagnostics、CRISPR and Genetic Engineering、Bacteriophages and microbial interactions