Effect of Fuzhengyiai recipe on serum IGF-1, EGF, TK1, CRP, CA199 and CD4+ lymphocyte subsets in patients after traditional radical resection of colon cancer

作者：Huafang Yin, Qiong Wang, Xia Sun, Ming Yuan, Dan Wu · 发表于：DOAJ (DOAJ: Directory of Open Access Journals) · 年份：2016 · 研究领域：Medicinal Plant Pharmacodynamics Research、Pharmacological Effects of Natural Compounds、Lipid metabolism and disorders

Objective: To study the effect of Fuzhengyiai recipe on serum IGF-1, EGF, TK1, CRP,
\nCA199 and CD4+ lymphocyte subsets in patients after traditional radical resection of colon
\ncancer. Methods: A total of 120 patients with colon cancer in our hospital from January
\n2013 to December 2015 were enrolled in this study. The subjects were divided into control
\ngroup (n=60) and experiment group (n=60) randomly. The control group were treated with
\ncapecitabine and oxaliplatin on the basis of the traditional radical resection of colon cancer,
\nthe experiment group were treated with Fuzhengyiai recipe on the basis of the control group.
\n21 days for a period of treatment and the two groups were treated for 3 periods. The serum
\nIGF-1, EGF, TK1, CRP, CA19-9 level and peripheral blood CD3+, CD4+, CD8+ and NK
\ncells of the two groups before and after treatment were compared. Results: There were no
\nsignificantly differences of the serum IGF-1, EGF, TK1,CRP, CA199 level and peripheral
\nblood CD3+, CD4+, CD8+ and NK cells of the two groups before treatment. The serum IGF-1,
\nEGF, TK1, CRP and CA19-9 level of the two groups after treatment were significantly lower
\nthan before treatment, and that of experiment were significantly lower than control group. The
\nperipheral blood CD3+, CD4+, CD8+ and NK cells of the control group were significantly lower
\nthan before treatment, and that of experiment were significantly hi...