What are the determinants of antiretroviral therapy adherence among stable people living with HIV? A cross-sectional study in Cambodia

作者：Sovannary Tuot, Jian Wei Sim, Michiko Hayashi, Pheak Chhoun, Alvin Kuo Jing Teo, Kiesha Prem, Siyan Yi · 发表于：AIDS Research and Therapy · 年份：2023 · DOI：10.1186/s12981-023-00544-w · 被引用次数：22 · 研究领域：HIV/AIDS Research and Interventions、HIV-related health complications and treatments、HIV/AIDS drug development and treatment

BACKGROUND: Understanding context-specific determinants of antiretroviral therapy (ART) adherence is crucial for developing tailored interventions for improving health outcomes and achieving the UNAIDS' third 95% target. This cross-sectional study explores factors associated with ART adherence among stable people living with HIV on ART in Cambodia. METHODS: We used baseline survey data from a quasi-experimental study conducted in 2021. The participants were recruited from 20 ART clinics in nine provinces for face-to-face interviews. A structured questionnaire collected information on sociodemographic characteristics, ART adherence, perceived ART self-efficacy, mental health, quality of life, stigma, and discrimination. We conducted bivariate and multiple logistic regression analyses to identify factors associated with ART adherence. RESULTS: Out of the 4101 participants, 86.5% reported adhering to ART in the past two months. The adjusted odds of ART adherence were significantly higher among participants in older age groups than those aged 15-29, participants with elevated cholesterol than those without it, participants who exhibited strong self-efficacy in health responsibility to maintain life than those with poor self-efficacy in health responsibility, participants who scored < 3 on the stigma and discrimination scale than those who scored ≥ 3, participants who scored ≥ 42 on the mental component of the quality-of-life scale than those who scored < 42. The adjusted odds of ...