Hemostasis Strategies and Recent Advances in Nanomaterials for Hemostasis

作者：Jian Du, Jing-Zhong Wang, Tao Xu, Hai Yao, Lili Yu, Da Huang · 发表于：Molecules · 年份：2023 · DOI：10.3390/molecules28135264 · 被引用次数：64 · 研究领域：Hemostasis and retained surgical items、Surgical Sutures and Adhesives、Electrospun Nanofibers in Biomedical Applications

The development of materials that effectively stop bleeding and prevent wound adhesion is essential in both military and medical fields. However, traditional hemostasis methods, such as cautery, tourniquets, and gauze, have limitations. In recent years, new nanomaterials have gained popularity in medical and health fields due to their unique microstructural advantages. Compared to traditional materials, nanomaterials offer better adhesion, versatility, and improved bioavailability of traditional medicines. Nanomaterials also possess advantages such as a high degree and stability, self-degradation, fewer side effects, and improved wound healing, which make them ideal for the development of new hemostatic materials. Our review provides an overview of the currently used hemostatic strategies and materials, followed by a review of the cutting-edge nanomaterials for hemostasis, including nanoparticles and nanocomposite hydrogels. The paper also briefly describes the challenges faced by the application of nanomaterials for hemostasis and the prospects for their future development.