The role of cannabidiol in aging

作者：Beibei Ni, Yanying Liu, Meng Dai, Jun Zhao, Liang Yu, Xue Yang, Bing Han, Man Jiang · 发表于：Biomedicine & Pharmacotherapy · 年份：2023 · DOI：10.1016/j.biopha.2023.115074 · 被引用次数：22 · 研究领域：Cannabis and Cannabinoid Research、Coffee research and impacts、Diet, Metabolism, and Disease

Aging is usually considered a key risk factor associated with multiple diseases, such as neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden of age-related diseases has become a global challenge. It is of great significance to search for drugs to extend lifespan and healthspan. Cannabidiol (CBD), a natural nontoxic phytocannabinoid, has been regarded as a potential candidate drug for antiaging. An increasing number of studies have suggested that CBD could benefit healthy longevity. Herein, we summarized the effect of CBD on aging and analyzed the possible mechanism. All these conclusions may provide a perspective for further study of CBD on aging.