Medication adherence trajectory of patients with chronic diseases and its influencing factors: A systematic review

作者：Yu Chen, Jing Gao, Minmin Lu · 发表于：Journal of Advanced Nursing · 年份：2023 · DOI：10.1111/jan.15776 · 被引用次数：33 · 研究领域：Medication Adherence and Compliance、Chronic Disease Management Strategies、Mobile Health and mHealth Applications

AIMS: To synthesize the published studies on medication adherence trajectories among patients with chronic diseases and identify the influencing factors. DESIGN: Systematic review. DATA SOURCES: Medline (Ovid), Embase (Ovid) and Web of Science core collection were searched from database inception to 1 July 2022. REVIEW METHODS: Potentially eligible articles were independently screened by three reviewers using set inclusion and exclusion criteria. The Joanna Briggs Institute critical appraisal checklist for cohort studies was used to appraise the quality of the included articles. Three reviewers independently evaluated the quality, extracted data and resolved differences by consensus. Results were presented using descriptive synthesis, and the prevalence of recategorised medication adherence trajectories was calculated from the published data. RESULTS: Fifty studies were included. Medication adherence trajectories among patients with chronic diseases were synthesized into six categories: adherence, non-adherence, decreasing adherence, increasing adherence, fluctuating adherence and moderate adherence. Low and moderate evidence showed that (1) patient-related factors, including age, sex, race, marital status and mental status; (2) healthcare team and system-related factors, including healthcare utilization, insurance and primary prescriber specialty; (3) socioeconomic factors including education, income and employment status; (4) condition-related factors including complication...