MiR-552-3p Regulates Multiple Fibrotic and Inflammatory genes Concurrently in Hepatic Stellate Cells Improving NASH-associated Phenotypes

作者：Ningning Ma, Aijun Hou, Xiangyu Pan, Fuguang Sun, Xiaoding Xu, Chuwei Yu, Rongtao Lai, Ruimin Huang, Likun Gong, Qing Xie, Jing Chen, Jin Ren · 发表于：International Journal of Biological Sciences · 年份：2023 · DOI：10.7150/ijbs.80760 · 被引用次数：8 · 研究领域：Liver Disease Diagnosis and Treatment、Liver physiology and pathology、Liver Diseases and Immunity

)-treated liver fibrosis model. In conclusion, miR-552-3p plays a crucial role in the pathogenesis of NASH by limiting multiple fibrotic and inflammatory pathways in HSCs, which may shed light on its therapeutic potential in NASH.