Application of Nanotechnology in Therapeutic Cancer Vaccines

作者：Jianmei Guo, Lin Tang, Kelin Li, Qingxin Ma, Shuda Luo, Ruoyu Cheng, Chaoyong Liu · 发表于：Advanced NanoBiomed Research · 年份：2023 · DOI：10.1002/anbr.202200122 · 被引用次数：16 · 研究领域：Immunotherapy and Immune Responses、RNA Interference and Gene Delivery、Nanoplatforms for cancer theranostics

Cancer vaccines stimulate the immune system within the body by introducing tumor antigens in various forms, such as tumor cells, tumor‐related proteins or peptides, and genes expressing tumor antigens, into the body. This activation of the immune response aims to prevent or treat tumors. Preventive cancer vaccines are primarily targeted at cancers caused by viral infections, and most cancer vaccines are currently designed as therapeutic vaccines for cancer treatment. In this review, the development of cancer vaccines, the mechanism of action, the types of antigens, and the progress of nanotechnology in therapeutic cancer vaccines are summarized. The development and application of cancer vaccines incorporating tumor‐specific antigens and nanomaterials are anticipated.