Boryl Radical-Promoted Deoxygenative Alkylation of Benzyl Acetates

作者：Feng‐Lian Zhang, Yi‐Feng Wang, Nannan Liu, Xuan-Chen Wan, Li-Wen Hui · 发表于：Synthesis · 年份：2023 · DOI：10.1055/s-0042-1751463 · 被引用次数：2 · 研究领域：Radical Photochemical Reactions、Catalytic C–H Functionalization Methods、Oxidative Organic Chemistry Reactions

Abstract Deoxygenative alkylation of benzyl alcohols was realized by using acetate as the alcohol activation group. The C–O bond homolysis is achieved by a boryl radical-promoted β-scission process. The strategy is amenable to a variety of benzyl alcohols, including primary, secondary, and more challenging tertiary alcohols. The synthetic practicability was demonstrated by a gram-scale one-pot reaction.