Prevalence, risk factors, impact and management of pneumonia among preschool children in Chinese seven cities: a cross-sectional study with interrupted time series analysis

作者：Haonan Shi, Tingting Wang, Zhuohui Zhao, Dan Norbäck, Xiaowei Wang, Yongsheng Li, Qihong Deng, Chan Lu, Xin Zhang, Xiaohong Zheng, Hua Qian, Ling Zhang, Wei Yu, Yuqing Shi, Tianyi Chen, Huaijiang Yu, Huizhen Qi, Ye Yang, Lan Jiang, Yuting Lin, Jian Yao, Junwen Lu, Qi Yan, for the China, Children, Homes, Health (CCHH) Study Group · 发表于：BMC Medicine · 年份：2023 · DOI：10.1186/s12916-023-02951-2 · 被引用次数：15 · 研究领域：Pneumonia and Respiratory Infections、Respiratory viral infections research、Pediatric health and respiratory diseases

BACKGROUND: Pneumonia is a common disease worldwide in preschool children. Despite its large population size, China has had no comprehensive study of the national prevalence, risk factors, and management of pneumonia among preschool children. We therefore investigated the prevalence of pneumonia among preschool children in Chinese seven representative cities, and explore the possible risk factors of pneumonia on children, with a view to calling the world's attention to childhood pneumonia to reduce the prevalence of childhood pneumonia. METHODS: Two group samples of 63,663 and 52,812 preschool children were recruited from 2011 and 2019 surveys, respectively. Which were derived from the cross-sectional China, Children, Homes, Health (CCHH) study using a multi-stage stratified sampling method. This survey was conducted in kindergartens in seven representative cities. Exclusion criteria were younger than 2 years old or older than 8 years old, non-permanent population, basic information such as gender, date of birth and breast feeding is incomplete. Pneumonia was determined on the basis of parents reported history of clearly diagnosed by the physician. All participants were assessed with a standard questionnaire. Risk factors for pneumonia, and association between pneumonia and other respiratory diseases were examined by multivariable-adjusted analyses done in all participants for whom data on the variables of interest were available. Disease management was evaluated by the paren...