A review of Benzimidazole derivatives#39; potential activities

作者：Amit Saini, G. V. S. R. Pavan Kumar, Gyan Singh · 发表于：International Journal of Pharmaceutical and Clinical Research · 年份：2023 · DOI：10.33545/26647591.2023.v5.i1a.51 · 被引用次数：3 · 研究领域：Synthesis and biological activity、Multicomponent Synthesis of Heterocycles、Synthesis and Characterization of Heterocyclic Compounds

Benzimidazole derivatives are a class of molecules with various biological properties that have received medicinal chemistry attention. This review addresses benzimidazole derivatives' drug discovery and development potential. Anticancer, antibacterial, anti-inflammatory, antiviral, and antiparasitic actions are reviewed. The structure-activity relationship (SAR) and mechanisms of benzimidazole derivatives are also discovered. Benzimidazole derivatives with therapeutic purposes are also emphasised. This review discusses the therapeutic uses of benzimidazole derivatives. It aids researchers, medicinal chemists, and pharmaceutical scientists in developing innovative benzimidazole-based medications. This review can aid in discovering new lead compounds and optimising existing benzimidazole derivatives for enhanced therapeutic efficacy.