Editorial: Vascular co-option and beyond for cancer biology

作者：Francesco Pezzella, Chao‐Nan Qian · 发表于：Frontiers in Oncology · 年份：2023 · DOI：10.3389/fonc.2023.1227540 · 被引用次数：4 · 研究领域：Angiogenesis and VEGF in Cancer、Cancer Research and Treatments、Cancer Genomics and Diagnostics

Since this Research Topic was launched, the third paper on the Hallmarks of Cancer has been published (1). In the first version, published in the year 2000, the authors wrote that "those researching the cancer problem will be practicing a dramatically different type of science than we have experienced over the past 25 years. Surely much of this change will be apparent at the technical level. But ultimately, the more fundamental change will be conceptual" (2), and this is reflected in the successive revised versions (1, 3). Among the conceptual changes that actually occurred, the paradigm switch summarized by the substitution of "inducing angiogenesis" with "inducing or accessing vasculature" is possibly the major one.