Predicting post-operative vault and optimal implantable collamer lens size using machine learning based on various ophthalmic device combinations

作者：Xi Chen, Yiming Ye, Huan Yao, Chang Liu, Anqi He, Xiangtao Hou, Keming Zhao, Zedu Cui, Yan Li, Jin Qiu, Pei Chen, Ying Yang, Jing Zhuang, Keming Yu · 发表于：BioMedical Engineering OnLine · 年份：2023 · DOI：10.1186/s12938-023-01123-w · 被引用次数：27 · 研究领域：Corneal surgery and disorders、Ophthalmology and Visual Impairment Studies、Intraocular Surgery and Lenses

BACKGROUND: Implantable Collamer Lens (ICL) surgery has been proven to be a safe, effective, and predictable method for correcting myopia and myopic astigmatism. However, predicting the vault and ideal ICL size remains technically challenging. Despite the growing use of artificial intelligence (AI) in ophthalmology, no AI studies have provided available choices of different instruments and combinations for further vault and size predictions. This study aimed to fill this gap and predict post-operative vault and appropriate ICL size utilizing the comparison of numerous AI algorithms, stacking ensemble learning, and data from various ophthalmic devices and combinations. RESULTS: = 0.499 (95% CI 0.470-0.528), mean absolute error = 130.655 (95% CI 128.949-132.111), accuracy = 0.895 (95% CI 0.883-0.907), AUC = 0.928 (95% CI 0.916-0.941)]. Sulcus-to-sulcus (STS), a parameter from UBM, ranked among the top five significant contributors to both post-operative vault and optimal ICL size prediction, consistently outperforming white-to-white (WTW). Moreover, dual-device combinations or single-device parameters could also effectively predict vault and ideal ICL size, and excellent ICL selection prediction was achievable using only UBM parameters. CONCLUSIONS: Strategies based on multiple machine learning algorithms for different ophthalmic devices and combinations are applicable for vault predicting and ICL sizing, potentially improving the safety of the ICL implantation. Moreover, our f...