ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

作者：Giacomo Grasselli, Carolyn S. Calfee, Luigi Camporota, Daniele Poole, Marcelo B. P. Amato, Massimo M. Antonelli, Yaseen M. Arabi, Francesca Baroncelli, Jeremy R. Beitler, Giacomo Bellani, Geoff J. Bellingan, Bronagh Blackwood, Lieuwe D. J. Bos, Laurent Brochard, Daniel Brodie, Karen E. A. Burns, Alain Combes, Sonia D’Arrigo, Daniel De Backer, Alexandre Demoule, Sharon Einav, Eddy Fan, Niall D. Ferguson, Jean‐Pierre Frat, Luciano Gattinoni, Claude Guérin, Margaret S. Herridge, Carol Lynette Hodgson, Catherine Lee Hough, Samir Jaber, Nicole Petra Juffermans, Christian Karagiannidis, Jozef Kesecioğlu, Arthur Kwizera, John Gerard Laffey, Jordi Mancebo, Michael A. Matthay, Daniel Francis McAuley, Alain Mercat, Nuala J. Meyer, Marc M. Moss, Laveena Munshi, Sheila Nainan Myatra, Michelle Ng Gong, Laurent Papazian, Bhakti K. Patel, Mariangela Pellegrini, Anders Perner, Antonio Pesenti, Lise Piquilloud, Haibo Qiu, Marco V. Ranieri, Elisabeth D. Riviello, A. S. Slutsky, Renee D. Stapleton, Charlotte Summers, Taylor B. Thompson, Carmen Sílvia Valente Barbas, Jesús Villar, Lorraine B. Ware, Björn Weiß, Fernando Godinho Zampieri, Élie Azoulay, Maurizio Cecconi, the European Society of Intensive Care Medicine Taskforce on ARDS · 发表于：Intensive Care Medicine · 年份：2023 · DOI：10.1007/s00134-023-07050-7 · 被引用次数：968 · 研究领域：Respiratory Support and Mechanisms、Intensive Care Unit Cognitive Disorders、Cardiac Arrest and Resuscitation

The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical pract...