K 2 CO 3 -promoted synthesis of amides from 1-aryl-2,2,2-trifluoroethanones and amines under mild conditions

作者：Pinyong Zhong, Yu-Chao Wang, Jin‐Biao Liu, Linjun Zhang, Nianhua Luo · 发表于：RSC Advances · 年份：2023 · DOI：10.1039/d3ra03329e · 被引用次数：9 · 研究领域：Chemical Synthesis and Analysis、Chemical Synthesis and Reactions、Advanced Synthetic Organic Chemistry

C(O)-C bond cleavage occurs without the use of any stoichiometric chemical oxidants or transition-metal catalysts. A series of primary and secondary amines are shown to be compatible with this transformation, and several pharmaceutical molecules were synthesized.