Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

作者：Assaf Magen, Pauline Hamon, Nathalie Fiaschi, Brian Y. Soong, Matthew D. Park, Raphaël Mattiuz, Étienne Humblin, Leanna Troncoso, Darwin D’souza, Travis Dawson, Joel Kim, Steven Hamel, Mark Buckup, Christie Chang, Alexandra Tabachnikova, Hara Schwartz, Nausicaa Malissen, Yonit Lavin, Alessandra Soares‐Schanoski, Bruno Giotti, Samarth Hegde, Giorgio Ioannou, Edgar Gonzalez‐Kozlova, C. Hennequin, Jessica Le Bérichel, Zhen Zhao, Stephen C. Ward, Isabel Fiel, Baijun Kou, Michael Dobosz, Lianjie Li, Christina Adler, Min Ni, Yi Wei, Wei Wang, Gurinder S. Atwal, Kunal Kundu, Kamil J. Cygan, Alexander M. Tsankov, Adeeb Rahman, Colles Price, Nicolás Fernández, Jiang He, Namita T. Gupta, Seunghee Kim‐Schulze, Sacha Gnjatic, Ephraim Kenigsberg, Raquel P. Deering, Myron Schwartz, Thomas U. Marron, Gavin Thurston, Alice O. Kamphorst, Miriam Mérad · 发表于：Nature Medicine · 年份：2023 · DOI：10.1038/s41591-023-02345-0 · 被引用次数：424 · 研究领域：Cancer Immunotherapy and Biomarkers、Immunotherapy and Immune Responses、Immune Cell Function and Interaction