The Impact of Growth Years on the Medicinal Material Characteristics and Metabolites of Stellaria dichotoma L. var. lanceolata Bge. Reveals the Optimal Harvest Age

作者：Zhenkai Li, Lu Feng, Hong Wang, Lin Zhang, Haishan Li, Yanqing Li, Pilian Niu, Gege Tian, Yan Yang, Xiangui Mei, Li Peng · 发表于：Plants · 年份：2023 · DOI：10.3390/plants12122286 · 被引用次数：15 · 研究领域：Traditional Chinese Medicine Analysis、Phytochemistry and Biological Activities、Metabolomics and Mass Spectrometry Studies

Bge (abbreviated as SDL). SDL is a perennial herbaceous plant and a characteristic crop in Ningxia. Growth years are vital factors that affect the quality of perennial medicinal materials. This study aims to investigate the impact of growth years on SDL and screen for the optimal harvest age by comparing the medicinal material characteristics of SDL with different growth years. Additionally, metabolomics analysis using UHPLC-Q-TOF MS was employed to investigate the impact of growth years on the accumulation of metabolites in SDL. The results show that the characteristics of medicinal materials and the drying rate of SDL gradually increase with the increase in growth years. The fastest development period of SDL occurred during the first 3 years, after which the development slowed down. Medicinal materials characteristics of 3-year-old SDL exhibited mature qualities with a high drying rate, methanol extract content, and the highest content of total sterols and total flavonoids. A total of 1586 metabolites were identified, which were classified into 13 major classes with more than 50 sub-classes. Multivariate statistical analysis indicated significant differences in the diversity of metabolites of SDL in different growth years, with greater differences observed in metabolites as the growth years increased. Moreover, different highly expressed metabolites in SDL at different growth years were observed: 1-2 years old was beneficial to the accumulation of more lipids, while 3-5 yea...