Research Progress of Dendritic Cell Surface Receptors and Targeting

作者：Chunyu Tong, Yimin Liang, Xianle Han, Zhelin Zhang, Xiaohui Zheng, Sen Wang, Bocui Song · 发表于：Biomedicines · 年份：2023 · DOI：10.3390/biomedicines11061673 · 被引用次数：16 · 研究领域：Immunotherapy and Immune Responses、Immune Cell Function and Interaction、T-cell and B-cell Immunology

Dendritic cells are the only antigen-presenting cells capable of activating naive T cells in humans and mammals and are the most effective antigen-presenting cells. With deepening research, it has been found that dendritic cells have many subsets, and the surface receptors of each subset are different. Specific receptors targeting different subsets of DCs will cause different immune responses. At present, DC-targeted research plays an important role in the treatment and prevention of dozens of related diseases in the clinic. This article focuses on the current status of DC surface receptors and targeted applications.