An Exploratory Study on a New Method for Nutritional Status Assessment in Patients with Chronic Kidney Disease

作者：Yayong Luo, Huang Hui, Qian Wang, Wenwen Lin, Shuwei Duan, Jianhui Zhou, Jing Huang, Weiguang Zhang, Ying Zheng, Li Tang, Xueying Cao, Jian Yang, Li Zhang, Yong Wang, Jie Wu, Guangyan Cai, Zheyi Dong, Xiangmei Chen · 发表于：Nutrients · 年份：2023 · DOI：10.3390/nu15112640 · 被引用次数：11 · 研究领域：Nutrition and Health in Aging、Dialysis and Renal Disease Management、Body Composition Measurement Techniques

Malnutrition is a risk factor for disease progression and poor prognosis in chronic kidney disease (CKD). However, the complexity of nutritional status assessment limits its clinical application. This study explored a new method of nutritional assessment in CKD (stage 1–5) patients using the Subjective Global Assessment (SGA) as the gold standard and evaluated its applicability. The kappa test was used to analyze the consistency of the Renal Inpatient Nutrition Screening Tool (Renal iNUT) with SGA and protein-energy wasting. Logistic regression analysis was used to analyze the risk factors of CKD malnutrition and calculate the prediction probability of multiple indicators combined for the diagnosis of CKD malnutrition. The receiver operating characteristic curve of the prediction probability was drawn to evaluate its diagnostic efficiency. A total of 161 CKD patients were included in this study. The prevalence of malnutrition according to SGA was 19.9%. The results showed that Renal iNUT had a moderate consistency with SGA and a general consistency with protein-energy wasting. Age > 60 years (odds ratio, OR = 6.78), neutrophil–lymphocyte ratio > 2.62 (OR = 3.862), transferrin < 200 mg/dL (OR = 4.222), phase angle < 4.5° (OR = 7.478), and body fat percentage < 10% (OR = 19.119) were risk factors for malnutrition in patients with CKD. The area under the receiver operating characteristic curve of multiple indicators for the diagnosis of CKD malnutrition was 0.89 (...