Decrease of Muscle Mass in Young Patients With Neuromuscular Disease: Assessment of Sarcopenia

作者：Jisoo Kim, Haesung Yoon, Hyun Ji Lim, Hyun Woo Kim, Yong June Suk, Kun-Bo Park, Mi‐Jung Lee · 发表于：Journal of Korean Medical Science · 年份：2023 · DOI：10.3346/jkms.2023.38.e187 · 被引用次数：9 · 研究领域：Cerebral Palsy and Movement Disorders、Scoliosis diagnosis and treatment、Nutrition and Health in Aging

BACKGROUND: Sarcopenia can be associated with the disease etiologies other than degenerative processes, such as neurologic disease including cerebral palsy, myelomeningocele, or Duchenne muscular dystrophy, even in children. Although the relationship between neurologic disease and scoliosis or ambulatory function is known, the mediators affecting scoliosis or gait function in these patients are unclear, an example might be sarcopenia. This study aimed to assess the degree of sarcopenia in young patients with neurologic diseases using computed tomography (CT), and analyze the correlation between sarcopenia and scoliosis or ambulatory function. METHODS: -test, Fisher's exact test, and logistic regression analyses were performed. RESULTS: = 0.004). CONCLUSION: Patients with neurologic diseases could have sarcopenia even in young age. Psoas muscle volume was also associated with ambulatory function in these patients. Sarcopenia was more severe in severe scoliosis patients in the non-ambulatory subgroup.