Identification of Growth-Related SNPs and Genes in the Genome of the Pearl Oyster (Pinctada fucata) Using GWAS

作者：Mingming Zhao, Wipavee Thaimuangphol, Yujie Hong, Ziqi Yan, Zongfa Chen, Minxuan Jin, Anna Zheng, Bei Wang, Zhongliang Wang · 发表于：Fishes · 年份：2023 · DOI：10.3390/fishes8060296 · 被引用次数：6 · 研究领域：Marine Bivalve and Aquaculture Studies、Genetic and phenotypic traits in livestock、Aquaculture Nutrition and Growth

Pinctada fucata, the pearl oyster, is a bivalve primarily cultivated for the production of saltwater pearls. In this study, the genome-wide association study (GWAS) for the growth-related traits and a principal components analysis (PCA) in P. fucata were performed. Genomic parameters of 6 growth-related traits in 60 individuals were estimated by using 4,937,162 single-nucleotide polymorphisms (SNPs). A total of 45 SNPs associated with growth traits were thus identified. Furthermore, 165 candidate genes were identified, including collagen alpha-3 (VI), serine/threonine-protein kinase mos-like harboring significant markers, and histidine-rich protein PFHRP-III-like, which may influence growth-related traits associated with various biological processes. The results of this study can facilitate marker-assisted selection and breeding programs designed to enhance growth and also offer a theoretical foundation for the further development and utilization of genomic resources in P. fucata.